October 2007 | Organized Symposia:, "Outdoor and Indoor Considerations of Atmospheric Aging on Exposure to Atmospheric Pollutants" K.G. Sexton, J.D. McDonald. The 17th Annual Conference of the International Society of Exposure Analysis, Durham, NC, Marriott Convention Center. 2007 Oct 17.
Following are Presentations from this Symposia:
Differentiating the Toxicity Induced By Photochemical Transformations of HAPS: The Role of Ozone and other Transformation Products, M. L. Doyle (Lovelace Respiratory Research Institute, Albuquerque, NM) , K. G. Sexton, I. Jaspers, H. E. Jeffries, K. de Bruijne, S. Ebersviller.
Smog Chamber Toxicology System to Study the Effects of Photochemical Aging of Urban Mixtures, K. G. Sexton, H. E. Jeffries, M. L. Doyle (Lovelace Respiratory Research Institute, Albuquerque, NM), K. deBruijne, S. Ebersviller, I. Jaspers.
Comparing the Toxicity of Fresh and Aged Diesel Exhaust Using a Newly Developed in vitro Exposure System, K. de Bruijne, K. G. Sexton, M. L. Doyle (Lovelace Respiratory Research Institute, Albuquerque, NM), S. Ebersviller, H. Jeffries, I. Jaspers.
Realistic Atmospheric Aging Enhances Respiratory Toxicity of Diesel Emissions, E. N. Potts (Duke University, Durham, NC), K. deBruijne, S. Ebersviller, K. G. Sexton, I. Jaspers , William Foster (Duke University, Durham, NC).
Assessing Respiratory Health and Indoor Chemistry Impacts of General Purpose Cleaning Products Containing Solvents with Different Reactivities, S. Ebersviller, E.P. Naess (U.S. EPA. RTP, NC), K.G. Sexton, K. de Bruijne.
August 2007 | "Electrostatic Aerosol in Vitro Exposure System (EAVES) as an Alternative Exposure System for Mixtures of Gases and Particles." K. de Bruijne. Defense of Master's Thesis. University of North Carolina, Chapel Hill.
| June 2007 | "Health Effects of Air Pollution:Beyond the Criteria
Pollutants" Philip Bromberg, Ilona Jasper, Ken Sexton, Harvey Jeffries, W. Michael
Foster. Presentation by Philip Bromberg at Air Toxics Workshop II, "Air Toxics Research: Implications of
Research on Policies to Protect Public Health ", Session 1, 12 June 07
Mickey Leland Center, National Urban Air Toxics Research Center,
Houston, TX.
| May 2007 | "The UNC Atmospheric Simulation Chamber Toxicology System - Effects of Chemical Transformations In Complex Mixtures" Jeffries, H. E.; Sexton, K. G.; Ebersviller, S.; de Bruijne, K.; Potts, E., and Naess, E. Invited Teleconference Presentation, Sponsored by the Risk Assessment Specialty Section of the Society of Toxicology, U.S. Environmental Protection Agency, RTP, NC. 2007 May 9.
| March 2007 | "Development and testing of a chemical mechanism for atmospheric photochemical transformations of 1,3-butadiene." K.G. Sexton, M.L. Doyle, S. Ebersviller. Published in Chemico-Biological Interactions166(1-3):156-162. (20 March 2007).
| March 2007 | "Atmospheric Photochemical Transformations Enhance 1,3-Butadiene-induced Inflammatory Responses in Human Epithelial Cells: The role of ozone and other photochemical degradation products." M. Doyle, K.G. Sexton, H.E. Jeffries, K. de Bruijne, S. Ebersviller, I. Jaspers. Published in Chemico Biological Interactions166(1-3):163-169. (20 March 2007).
| March 2007 | "Comparing the Toxicity of Fresh and Aged Diesel Exhaust Using a Newly Developed in vitro Exposure System" (K. de Bruijne, K. Sexton, M. Doyle, S. Ebersviller, H. Jeffries, I. Jaspers) Poster presentation at Society of Toxicology 46th Annual Meeting , March 2007, Charlotte, NC.
| March 2007 | "Assessing Respiratory Health Impacts of General Purpose Cleaning Products Containing Solvents with Different Reactivities" (E. P. Naess, S. Ebersviller, K. Sexton, K. de Bruijne, M. Doyle, H. Jeffries) Poster presentation at Society of Toxicology 46th Annual Meeting , March 2007, Charlotte, NC.
| March 2007 | "Realistic Atmospheric Aging Enhances Respiratory Toxicity of Diesel Emissions" (E. Potts, K. deBruijne, S. Ebersviller, K. Sexton, I. Jaspers, W. Foster) Poster presentation at Society of Toxicology 46th Annual Meeting , March 2007, Charlotte, NC.
| February 2007 | "Indoor Chemistry and Respiratory Impacts of Cleaning Products: A look at d-Limonene" (E. Naess, S. Ebersviller, K. Sexton, M.L. Doyle, K. de Bruijne, H. Jeffries) Poster presented at the Gordon Conference, Biogenic Hydrocarbons and the Atmosphere. February 25 - March 2, 2007, Ventura, CA.
| February 2007 | The research group gave a Presentation on UNC One Atmosphere Research Program at the EPA in RTP, NC on February 5, 2007. The presentation gave an overview of the project, including a summary of new techniques developed and experimental findings to date, and suggestions for future research. Presenters included Dr. Harvey Jeffries, Dr. Ilona Jaspers, Dr. Ken Sexton, Professor Richard Kamens, Dr. Melanie Doyle, Seth Ebersviller, Kim deBruijne, Liz Naess, and Erin Potts. To view individual presentations, log on anonymously to http://ftpozone.sph.unc.edu and then navigate to /Library/UNC_docs/Presentations/By_Meetings/ OneAtmosphereWorkshopEPA_Feb_07/
| January 2007 | "Smog Under Glass" The rooftop smog chamber and One Atmosphere research program are profiled in Endeavors Magazine, UNC's Magazine of Research. Winter 2007 Endeavors Magazine, Office of the Vice Chancellor for Research and Economic Development, University of North Carolina at Chapel Hill.
| October 2006 | "Using Smog Chambers to Test Photochemical Transformation of HAPS and their Secondary Products" (M. Doyle, K. Sexton, I. Jaspers, K. de Bruijne, S. Ebersviller, H. Jeffries) Presentation given at the 2006 CRC Mobile Source Air Toxics Workshop October 23-25, 2006, Phoenix, AZ.
| September 2006 | "The University of North Carolina Chamber-Toxicology Laboratory for Studying Atmospheric Chemistry Effects on Toxicity of Air Pollution Mixtures" (K. Sexton) Poster presented at Environmental Partnership Summit (EPA, UNC, NCSU, AWMA) September 26-27, 2006, North Carolina Biotechnology Center Headquarters (Research Triangle Park) and Hamner Conference Center. Research Triangle Park, NC.
| September 2006 | "Electrostatic Precipitation as an Alternative method for In Vitro Exposures to Mixtures of Gases and Particles" (K. de Bruinje, S. Lake, K. Sexton, M. Doyle, S. Ebersviller, E. Naess, H, Jeffries, D. Leith, I. Jaspers ) - Poster presented at 2006 International Aerosol Conference organized by the American Asociation for Aerosol Research (AAAR) , Sept. 10-15, 2006, Minneapolis, MN.
| September 2006 | "A Comparison of the Oxidation Products and Secondary Organic Aerosol Formation Potential of
d-Limonene and an Off-the-shelf Cleaning Product Containing d-Limonene. " (S. Ebersviller, K.G. Sexton, E. Naess, K. Galloway, and H. Jeffries ) - Poster presented at 2006 International Aerosol Conference organized by the American Asociation for Aerosol Research (AAAR) , Sept. 10-15, 2006, Minneapolis, MN.
| March 2006 | "The Effect of Photochemical Aging on the Toxicity of Air Pollution Mixtures" (Sexton K. G., Doyle M., Jaspers I., Jeffries H. E. ) - Symposium presented at Society of Toxicology 45th Annual Meeting , March 5-9, 2006, San Diego, CA. in Symposium Session titled Air Pollution: Vanguard Toxicological Approaches Considering Atmospheric Aging , Jaspers I and Rohr A. co-chairs.
"Examining the Inflammatory Responses of HAPS: The Role of Ozone and other Photochemical Transformation Products" (Sexton K. G., M. Doyle, K. de Bruijne, S. Ebersviller, H. Jeffries, I. Jaspers, ) Poster presented at the 45th Annual Society of Toxicology Meeting, San Diego, CA, March 5-9, 2006.
"Repeated Exposures of Human Respiratory Epithelial Cells to Low Levels of Ozone Sensitizes the Effects induced by Subsequent Challenges to Ozone or HAPS" (Doyle M. , K. G. Sexton, K. de Bruijne, S. Ebersviller, H. Jeffries, I. Jaspers) Poster presented at the 45th Annual Society of Toxicology Meeting, San Diego, CA, March 5-9, 2006.
"Smog Chambers Coupled to In-Vitro and In-Vivo Gaseous Exposure Chambers for Assessing Exposure to Reactive Volatile Organic Compounds and Their Transformation Products" ( Sexton K. G., Doyle, M., Jeffries, H., Jaspers, I.) Poster presented at the 45th Annual Society of Toxicology Meeting, San Diego, CA, March 5-9, 2006.
"Electrostatic Precipitation as an Alternative Method for In Vitro Exposures to Mixtures of Gases and Particles" ( de Bruijne,K., Lake, S., Sexton K. G., Doyle, M., Ebersviller, S., Jeffries, H., Leith, D., Jaspers, I.) Poster presented at the 45th Annual Society of Toxicology Meeting, San Diego, CA, March 5-9, 2006.
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Oct. 2005 | "Smog Chambers: A Tool to examine effects of photochemically aged air in biological systems"
Presentation by Ken Sexton at the International Society of Exposure Analysis (ISEA) Annual Conference Tucson, AZ Oct 30 - Nov., 2005. "Smog Chamber Toxicology Better Estimates the True Toxic Potential of Atmospheric Mixtures"
Poster presented at International Society of Exposure Analysis (ISEA) Annual Conference Tucson, AZ. Poster and abstract, and Presentation slides are available in the Project Documents section of this website.
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Oct. 2005 | "Air Toxics: What We Know, What We Don't Know, and What We Need to Know"
Talk given by Harvey Jeffries at a Workshop for Researchers and Policymakers
organized by Mickey Leland National Urban Air Toxics Research Center (NUATRC) Oct. 17-18, 2005 in Houston, TX.
Presentation slides are available in the Project Documents section of this website.
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Sept. 2005 | "Development and Testing of a Chemical Mechanism for Atmospheric Photochemical Transformations of 1,3-Butadiene"
and
"Atmospheric Photochemical Transformations Enhance 1,3-Butadiene-induced Inflammatory Responses in Human Epithelial Cells: The role of ozone and other photochemical degradation products"
Two posters presented at IISRP International Symposium Evaluation of Butadiene & Chloroprene Health Risks Sept. 20-22, 2005, Charleston, SC. Posters and abstracts are available in the Project Documents section of this website.
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May 2005 | "The Role of Ozone and other Photochemical Transformation Products for Isoprene and Methanol: Examining the Inflammatory Responses in Human Respiratory Epithelial Cells", Doyle M., Sexton K. G., Jeffries H. E., Lichtveld K., Ebersviller S., and Jaspers I.; submitted for publication to Environmental Health Perspectives
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March 2005 | "Photochemical Reactions of Industrial Pollutants Enhance Cytotoxicity and Inflammatory Responses in Human Lung Cells"
and
"Zinc Deficiency Enhances Pro-Inflammatory Responses after Ozone Exposure"
Two posters presented at Society of Toxicology 44th Annual Meeting March 5-10, 2005, New Orleans, LA. Posters and abstracts are available in the Project Documents section of this website.
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Sept. 2004 | Melanie Doyle gives a presentation at EPA-RTP on her One Atmosphere project research, Sept. 23, 2004.
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August 2004 | Effects of 1-3-butadiene, isoprene, and the photchemical degradation products on human lung cells published in Environmental Health Perspectives
"Effects of 1-3-butadiene, Isoprene, and their Photochemical Degradation Products on Human Lung Cells", Doyle M., Sexton K. G., Jeffries H., Bridge K. and Jaspers I. Environmental Health Perspectives, 112(15):1488-1495, 2004.
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June 2004
and
July 2005 | Middle-Schoolers  from the Morehead Planetarium and Science Center Summer Camp visit the One Atmosphere rooftop smog chamber to learn about about atmospheric chemistry and toxicology, and about our ongoing research. More ...
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July 2004 | "Photochemical Products in Urban Mixtures Enhance Inflammatory Responses in Lung Cells" published in Inhalation Toxicology. Available online
"Photochemical Products in Urban Mixtures Enhance Inflammatory Responses in Lung Cells" Kenneth Sexton; Harvey Jeffries; Myoseon Jang; Richard Kamens; Melanie Doyle; Iuliana Voicu; Ilona Jaspers. Inhalation Toxicology Supplement 1/2004, vol. 16, no. Supplement 1 to Issue 1, pp. 107-114(8)
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May 2004 | "Innovative Experimental Techniques to Help  Understand Exposure to Volatile Organic Air Toxics"
Poster presented by Ken Sexton at the American Chemistry Council (ACC) Long Range Research Initiative (LRI), Second Annual Science Meeting, May 5-6, 2004, Miami, Florida. Poster and abstract are available in the Project Documents section of this website.
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March 2004 | "Effects of 1,3-Butadiene, Isoprene, and their Photochemical Degradation Products on Human Lung Cells"
Poster presented at Society of Toxicology 43rd Annual Meeting March 21 - March 25, 2004, Baltimore, MD.
Poster and abstract are available in the Project Documents section of this website.
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Feb. 2004 | The One Atmosphere research group held a half-day workshop on the UNC campus to share findings and progress on the project and to explore possible collaborations with synchronous research going on within EPA and other research areas on campus. Presentations were made on the progress of the particle cell exposure system, the status of the new rooftop chamber, and recent student thesis work and conference presentations, as well as future directions that the One Atmosphere project might take.Ê In attendance were researchers from EPA's National Exposure Research Lab, Office of Air Quality Planning and Standards, and National Health and Environmental Effects Research Laboratory; the Center for Environmental Medicine & Lung Biology of UNC School of Medicine, and UNC'S Department of Environmental Sciences and Engineering. Feb. 24, 2004.
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March 2003 | "Smog Chambers Experiments Of Urban Mixtures Enhance Inflammatory Responses In Lung Cells."
Poster presented at the specialty PM Meeting of The AAAR-PM 2003,March 31 - April 4, 2003, Pittsburgh
and peer-reviewed Paper accepted for Inhalation Toxicology for Proceedings Issue from the Pittsburgh Meeting. Poster and abstract are available in the Project Documents section of this website.
Sexton K.G., Jaspers I., Jeffries H.E., Jang M., Kamens R.M., Doyle M. and Voicu I., Smog Chambers Experiments Of Urban Mixtures Enhance Inflammatory Responses In Lung Cells. accepted by Inhalation Toxicology, special Proceedings Issue for AAAR-PM meeting, Pittsburgh, PA, October 3, 2003.
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March 2003 | "Photochemical Reactions of Urban Air Pollution Mixtures Enhance Inflammatory Responses in Lung Cells."
Poster presented at the Society of Toxicology 42nd Annual Meeting, Salt Lake City, UT.
Poster and abstract are available in the Project Documents section of this website.
Jaspers I., Jeffries H.E., Sexton K.G., Kamens R.M. and Doyle M., Photochemical Reactions Of Urban Air Pollution Mixtures Enhance Inflammatory Responses In Lung Cells. Poster presented at the Society of Toxicology Annual Meeting, 2003, Salt Lake City, Utah, Abstract in The Toxicologist , 72, 190, March 9-13, 2003.
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July-September. 2002 | Preliminary smog chamber/lung cell experiments conducted are conducted. Methodology and results from these experiments are outlined in abstracts available in the Project Documents section of the website.
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April 2002 | Currently recruiting post-docs and students for One Atmosphere Project
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April 10, 2002 | UNC submits proposal for Cooperative Agreement
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March 7, 2002 | EPA requests proposal from UNC for Cooperative Agreement
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Nov. 6, 2001 | Congress appropriates $1.5 million to the "University of North Carolina at Chapel Hill for the Schools of Public Health and Medicine to advance the one atmosphere approach to determining the health effects of air pollution" (US House Senate conference Report 07-272, 11/6/01)
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